PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30190369-2 2019 The phase III SHARP trial showed a median time-to-progression (mTTP) of 5.5 months, overall response rate (ORR) of 2%, and median overall survival (mOS) of 10.7 months with sorafenib. Sorafenib 173-182 Moloney sarcoma oncogene Mus musculus 148-151 30190369-13 2019 Shorter TTP and OS were associated with increases in Tregs and CD56Dim natural killer (NK) cells after sorafenib alone and plasma sMET after combination treatment (all P < 0.05). Sorafenib 103-112 Moloney sarcoma oncogene Mus musculus 16-18 31799203-12 2019 Conclusion: When comparing 2 periods of treatment in advanced HCC patients under sorafenib, duration of treatment and mOS were higher in the recent period. Sorafenib 81-90 Moloney sarcoma oncogene Mus musculus 118-121 26441378-2 2016 We investigated the effect of post-progression survival (PPS) and progression-free survival (PFS) on overall survival (OS) in patients whose advanced HCC was treated by sorafenib. Sorafenib 169-178 Moloney sarcoma oncogene Mus musculus 119-121 27299940-4 2016 The mOS increased 21% when the AAT was sorafenib (SOR) or 42% when locoregional therapy was coadministered. Sorafenib 39-48 Moloney sarcoma oncogene Mus musculus 4-7 27299940-4 2016 The mOS increased 21% when the AAT was sorafenib (SOR) or 42% when locoregional therapy was coadministered. Sorafenib 50-53 Moloney sarcoma oncogene Mus musculus 4-7 30395717-2 2018 In 2007, sorafenib became the first Food and Drug Administration (FDA) approved first line systemic treatment for HCC, however, it confers only modest benefit in median overall survival (mOS) and comes with significant side effects. Sorafenib 9-18 Moloney sarcoma oncogene Mus musculus 187-190 34000725-11 2021 mOS from 1st-line therapy with tyrosine kinase inhibitor plus sorafenib-regorafenib-lenvatinib was 29.5 months; that with lenvatinib-sorafenib-regorafenib was not obtained. Sorafenib 62-71 Moloney sarcoma oncogene Mus musculus 0-3