PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16458542-0 2006 Zoledronic acid is synergic with vinblastine to induce apoptosis in a multidrug resistance protein-1 dependent way: an in vitro study. Zoledronic Acid 0-15 ATP binding cassette subfamily B member 1 Homo sapiens 70-100 16458542-7 2006 This preliminary work shows that zoledronic acid acts synergistically with vinblastine to induce apoptosis in an MRP-1 dependent way. Zoledronic Acid 33-48 ATP binding cassette subfamily B member 1 Homo sapiens 113-118 25544757-6 2015 By decreasing the isoprenoid supply, zoledronic acid down-regulated the Ras/ERK1/2/HIF-1alpha/Pgp axis and chemosensitized the HMM cells to Pgp substrates. Zoledronic Acid 37-52 ATP binding cassette subfamily B member 1 Homo sapiens 94-97 25544757-6 2015 By decreasing the isoprenoid supply, zoledronic acid down-regulated the Ras/ERK1/2/HIF-1alpha/Pgp axis and chemosensitized the HMM cells to Pgp substrates. Zoledronic Acid 37-52 ATP binding cassette subfamily B member 1 Homo sapiens 140-143 25544757-10 2015 Thanks to its ability to decrease Ras/ERK1/2 activity, which is responsible for both Pgp-mediated chemoresistance and IDO-mediated immunosuppression, zoledronic acid is an effective chemo-immunosensitizing agent in HMM cells. Zoledronic Acid 150-165 ATP binding cassette subfamily B member 1 Homo sapiens 85-88