PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30534634-0 2018 The inhibitory effects of rosmarinic acid on catabolism induced by IL-1beta in rat chondrocyte. rosmarinic acid 26-41 interleukin 1 beta Rattus norvegicus 67-75 34314849-10 2021 RA treatment in a dose-dependent manner prevented the overproduction of tumor necrosis factor-alpha (TNF-alpha), interleukin 1 beta (IL-1beta), and IL-6 in both the HIP and PFC. rosmarinic acid 0-2 interleukin 1 beta Rattus norvegicus 113-131 25735949-3 2015 Oral administration of RA (100 mg/kg b.w) significantly (p < 0.05) increased the insulin sensitivity index (ISI0,120), while the levels of blood glucose, HbA1c, advanced glycation end products (AGE), TNF-alpha, IL-1beta, IL 6, NO, p-JNK, P38 MAPK and NF-kappaB were significantly reduced, with a concomitant elevation in the plasma insulin levels in diabetic rats. rosmarinic acid 23-25 interleukin 1 beta Rattus norvegicus 214-222 23548128-6 2013 The findings showed that RA inhibited Cd(2+) -mediated cell toxicity, reactive oxygen species generation, interleukin (IL)-6 and IL-1beta production, the translocation of the apoptosis inducing factor into the nucleus and activation of caspases-3 in an auditory cell line, HEI-OC1. rosmarinic acid 25-27 interleukin 1 beta Rattus norvegicus 129-137 26364660-5 2015 Pretreatment with RA significantly ameliorated pancreas histopathological changes, decreased amylase and lipase activities in serum, lowered myeloperoxidase activity in the pancreas, reduced systematic and pancreatic interleukin-1 beta (IL-1beta), IL-6, and tumor necrosis factor-alpha (TNF-alpha) levels, and inhibited NF-kappaB translocation in pancreas. rosmarinic acid 18-20 interleukin 1 beta Rattus norvegicus 217-235 26364660-5 2015 Pretreatment with RA significantly ameliorated pancreas histopathological changes, decreased amylase and lipase activities in serum, lowered myeloperoxidase activity in the pancreas, reduced systematic and pancreatic interleukin-1 beta (IL-1beta), IL-6, and tumor necrosis factor-alpha (TNF-alpha) levels, and inhibited NF-kappaB translocation in pancreas. rosmarinic acid 18-20 interleukin 1 beta Rattus norvegicus 237-245