PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21526214-8	2011	Pretreatment of RA inhibited caspase-1 downstream signal pathway, such as the activation of caspase-3 and 9, release of cytochrome c, translocation of apoptosis-inducing factor, up-regulation of Bax, down-regulation of Bcl-2, generation of reactive oxygen species, and activation of nuclear factor-kappaB.	rosmarinic acid	16-18	BCL2 associated X, apoptosis regulator	Homo sapiens	195-198	
18644421-3	2008	Rosmarinic acid effectively suppressed the up-regulation of Bax and down-regulation of Bcl-2.	rosmarinic acid	0-15	BCL2 associated X, apoptosis regulator	Homo sapiens	60-63	
32862580-5	2020	Western blot assay was used to study the effects of rosmarinic acid on apoptosis-related protein expressions including Bax, Bcl-2 and various caspases.	rosmarinic acid	52-67	BCL2 associated X, apoptosis regulator	Homo sapiens	119-122	
32862580-8	2020	The AO/EB staining assay showed that rosmarinic acid suppressed the viability of cancer cells via induction of apoptotic cell death which was associated with rise in Bax and decrease in Bcl-2 levels.	rosmarinic acid	37-52	BCL2 associated X, apoptosis regulator	Homo sapiens	166-169	
30200738-0	2018	[Effect of rosmarinic acid from Sarcandra glabra in inhibiting proliferation and migration and inducing apoptosis of MDA-MB-231 cells via regulation of expressions of Bcl-2 and Bax].	rosmarinic acid	11-26	BCL2 associated X, apoptosis regulator	Homo sapiens	177-180	
30200738-7	2018	The down-regulation of the Bcl-2 expression and the up-regulation of the Bax expression were observed in MDA-MB-231 cells after rosmarinic acid treatment.	rosmarinic acid	128-143	BCL2 associated X, apoptosis regulator	Homo sapiens	73-76	
30200738-8	2018	The results suggested that rosmarinicacid can inhibit the proliferation and migration, and induce the apoptosis of MDA-MB-231 cells, which may be correlated with the down-regulation of Bcl-2 gene and the up-regulation of Bax gene.	rosmarinic acid	27-41	BCL2 associated X, apoptosis regulator	Homo sapiens	221-224	
30453545-10	2018	In addition, RA modulated the protein expression of intrinsic mitochondrial apoptotic pathway-related genes, such as Bax, Bcl-2, caspase-3 and poly (ADP-ribose) polymerase 1 (PARP-1) (cleaved) via the upregulation of p53 derived from HDAC2 downregulation, leading to the increased apoptosis of PC-3 and DU145 cells.	rosmarinic acid	13-15	BCL2 associated X, apoptosis regulator	Homo sapiens	117-120