PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23756732-9	2013	RA might be a useful treatment for depression and the changes in ERK1/2 signaling and BDNF levels may play a critical role in the pharmacological action of RA.	rosmarinic acid	156-158	mitogen activated protein kinase 3	Rattus norvegicus	65-71	
24418162-4	2014	Interestingly, the effects of RA were inhibited by the blockage of the ERK signaling.	rosmarinic acid	30-32	mitogen activated protein kinase 3	Rattus norvegicus	71-74	
24418162-5	2014	These data support the use of RA for treating PTSD and indicate that the ERK1/2 signaling cascade may play a critical role in the therapeutic efficacy of RA in treating such conditions.	rosmarinic acid	154-156	mitogen activated protein kinase 3	Rattus norvegicus	73-79	
23085339-3	2013	In our previous study, we demonstrated that R. officinalis and its active compounds, luteolin (Lut), carnosic acid (CA), and rosmarinic acid (RA), exhibited neurotrophic effects and improved cholinergic functions in PC12 cells in correlation with mitogen-activated protein kinase (MAPK), ERK1/2 signaling pathway.	rosmarinic acid	125-140	mitogen activated protein kinase 3	Rattus norvegicus	281-285	
23085339-3	2013	In our previous study, we demonstrated that R. officinalis and its active compounds, luteolin (Lut), carnosic acid (CA), and rosmarinic acid (RA), exhibited neurotrophic effects and improved cholinergic functions in PC12 cells in correlation with mitogen-activated protein kinase (MAPK), ERK1/2 signaling pathway.	rosmarinic acid	125-140	mitogen activated protein kinase 3	Rattus norvegicus	288-294	
23085339-3	2013	In our previous study, we demonstrated that R. officinalis and its active compounds, luteolin (Lut), carnosic acid (CA), and rosmarinic acid (RA), exhibited neurotrophic effects and improved cholinergic functions in PC12 cells in correlation with mitogen-activated protein kinase (MAPK), ERK1/2 signaling pathway.	rosmarinic acid	142-144	mitogen activated protein kinase 3	Rattus norvegicus	281-285	
23085339-3	2013	In our previous study, we demonstrated that R. officinalis and its active compounds, luteolin (Lut), carnosic acid (CA), and rosmarinic acid (RA), exhibited neurotrophic effects and improved cholinergic functions in PC12 cells in correlation with mitogen-activated protein kinase (MAPK), ERK1/2 signaling pathway.	rosmarinic acid	142-144	mitogen activated protein kinase 3	Rattus norvegicus	288-294	
20633629-7	2010	U0126, inhibitor of ERK1/2, significantly reduced CA and RA effects on cell differentiation and AChE activity.	rosmarinic acid	57-59	mitogen activated protein kinase 3	Rattus norvegicus	20-26