PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33747209-7 2021 Then, ruxolitinib downregulated myeloid cell leukemia-1 (Mcl-1) mRNA level and decreased its protein level, which enabled Bak to trigger CRC apoptosis. ruxolitinib 6-17 BCL2 antagonist/killer 1 Homo sapiens 122-125 29928488-5 2018 However, inhibition of BCL-xL/BCL-2 by the BH3 mimetics ABT-737 and navitoclax or BCL-xL by A-1331852 induced caspase-dependent apoptosis involving activation of Bak and Bax synergistically with ruxolitinib in HEL cells. ruxolitinib 195-206 BCL2 antagonist/killer 1 Homo sapiens 162-165