PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25213670-6 2014 In cisplatin-resistant cells with higher Jak2 and STAT3 expression, cisplatin and ruxolitinib combination dramatically suppressed the cell growth, down-regulated the expression of phosphorylated STAT3 and induced cleaved caspase-3 expression. ruxolitinib 82-93 caspase 3 Homo sapiens 221-230 29436642-10 2018 Western blot analysis revealed that these synergistic effects of ruxolitinib and calcitriol were associated with reduced protein levels of JAK2, phosphorylated JAK2, c-Myc proto oncogene protein, cyclin-D1, apoptosis regulator Bcl-2 and Bcl-2-like protein 1, and with increased levels of caspase-3 and Bcl-2-associated agonist of cell death proteins. ruxolitinib 65-76 caspase 3 Homo sapiens 288-297