PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35218354-11 2022 Ruxolitinib blocks chemotaxis through inhibition of SG-MSC production of CXCL9, CXCL10, and CXCL11. ruxolitinib 0-11 C-X-C motif chemokine ligand 10 Homo sapiens 80-86 34422627-7 2021 Recombinant human CXCL10 induced JAK-STAT and PD-L1, while the CXCL10-CXCR3 and JAK-STAT inhibitors AMG487 or ruxolitinib reduced the expression of PD-L1 in HFF-1 cells. ruxolitinib 110-121 C-X-C motif chemokine ligand 10 Homo sapiens 63-69 32562787-11 2020 In this model, we showed that ruxolitinib significantly prevented the upregulation of pro-inflammatory M1 markers (TNFalpha, CXCL10, NOS2) and pro-fibrotic M2 markers (Arg1 and Chi3L3). ruxolitinib 30-41 C-X-C motif chemokine ligand 10 Homo sapiens 125-131 27892610-3 2017 Our results demonstrate that ruxolitinib significantly decreases the production of CLE-typical cytokines (CXCL10, CXCL9, MxA) and might be a promising drug for future clinical studies in patients with CLE and related autoimmune skin diseases. ruxolitinib 29-40 C-X-C motif chemokine ligand 10 Homo sapiens 106-112