PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28944880-13 2017 Furthermore, it was observed that edoxaban increased PI3K and AKT expression both in vitro and in vivo. edoxaban 34-42 AKT serine/threonine kinase 1 Rattus norvegicus 62-65 28944880-15 2017 In conclusion, these findings suggested that edoxaban can improve venous thrombosis by decreasing hydrogen sulfide and homocysteine through the PI3K/AKT signaling pathway. edoxaban 45-53 AKT serine/threonine kinase 1 Rattus norvegicus 149-152