PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30210674-5	2018	The levels of tumor necrosis factor alpha, interleukin 1 beta, and interleukin 6, as well as total protein and Evans blue concentrations, were all significantly reduced in bronchoalveolar lavage fluid from mice treated with rivaroxaban.	Rivaroxaban	224-235	tumor necrosis factor	Mus musculus	14-41	
33693223-8	2020	Rivaroxaban also downregulated the mRNA expression levels of tumor necrosis factor-alpha, transforming growth factor-beta, PAR-1 and PAR-2 in the infarcted area, and both A-type and B-type natriuretic peptides in the non-infarcted area compared with the vehicle.	Rivaroxaban	0-11	tumor necrosis factor	Mus musculus	61-88	
28993090-11	2018	TAC-induced protein overexpression of monocyte chemoattractant protein-1, and mRNA overexpression of tumor necrosis factor-alpha, interleukin (IL)-1beta and IL-6 in the left atrium was suppressed by RVX treatment.	Rivaroxaban	199-202	tumor necrosis factor	Mus musculus	101-128	
26370374-6	2015	In mouse cytokine array measuring 40 cytokines, the productions of interleukin-16, TIMP-1, and tumor necrosis factor-alpha (TNF-alpha) were significantly reduced with 0.1 mug/mL of rivaroxaban pretreatment (all P < 0.05).	Rivaroxaban	181-192	tumor necrosis factor	Mus musculus	95-122	
26370374-6	2015	In mouse cytokine array measuring 40 cytokines, the productions of interleukin-16, TIMP-1, and tumor necrosis factor-alpha (TNF-alpha) were significantly reduced with 0.1 mug/mL of rivaroxaban pretreatment (all P < 0.05).	Rivaroxaban	181-192	tumor necrosis factor	Mus musculus	124-133	
21772662-7	2011	Real time-PCR from thoracic aortas revealed that rivaroxaban (5 mg/kg/day) treatment reduced mRNA expression of inflammatory mediators, such of IL-6, TNF-alpha, MCP-1, and Egr-1 (P < .05).	Rivaroxaban	49-60	tumor necrosis factor	Mus musculus	150-159	
29269019-7	2018	Quantitative RT-PCR analyses demonstrated that rivaroxaban reduced the expression of inflammatory molecules (e.g., IL-1beta and TNF-alpha) in injured arteries at seven days after surgery (P<0.05, respectively).	Rivaroxaban	47-58	tumor necrosis factor	Mus musculus	128-137	
29269019-8	2018	In vitro experiments using mouse peritoneal macrophages demonstrated that FXa increased the expression of inflammatory molecules (e.g., IL-1beta and TNF-alpha), which was blocked in the presence of rivaroxaban (P<0.05).	Rivaroxaban	198-209	tumor necrosis factor	Mus musculus	149-158