PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32271680-0 2020 Response by Petzold et al to Letter Regarding Article, "Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa-Driven Platelet Activation via Protease Activated Receptor-1". Rivaroxaban 56-67 coagulation factor II thrombin receptor Homo sapiens 148-178 33788669-2 2021 It was recently shown that FXa induces platelet aggregation via protease activated receptor 1 (PAR-1) which is in turn attenuated by rivaroxaban. Rivaroxaban 133-144 coagulation factor II thrombin receptor Homo sapiens 64-93 33788669-2 2021 It was recently shown that FXa induces platelet aggregation via protease activated receptor 1 (PAR-1) which is in turn attenuated by rivaroxaban. Rivaroxaban 133-144 coagulation factor II thrombin receptor Homo sapiens 95-100 32379576-0 2020 Letter by Violi et al Regarding Article, "Rivaroxaban Reduces Arterial Thrombosis by Inhibition of Fxa-Driven Platelet Activation via Protease Activated Receptor-1". Rivaroxaban 42-53 coagulation factor II thrombin receptor Homo sapiens 134-164 32379578-0 2020 Response by Petzold et al to Letter Regarding Article, "Rivaroxaban Reduces Arterial Thrombosis by Inhibition of Fxa-Driven Platelet Activation via Protease Activated Receptor-1". Rivaroxaban 56-67 coagulation factor II thrombin receptor Homo sapiens 148-178 32271683-0 2020 Letter by Borst Regarding Article, "Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa Driven Platelet Activation via Protease Activated Receptor-1". Rivaroxaban 36-47 coagulation factor II thrombin receptor Homo sapiens 128-158 28035779-9 2017 It is suggested that the relative downregulation of PAR-1 and PAR-2 by rivaroxaban compared with warfarin pretreatment might be partly involved in the mechanism of reduced hemorrhagic complications in patients receiving rivaroxaban in clinical trials. Rivaroxaban 71-82 coagulation factor II thrombin receptor Homo sapiens 52-57 31859592-0 2020 Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa-Driven Platelet Activation via Protease Activated Receptor-1. Rivaroxaban 0-11 coagulation factor II thrombin receptor Homo sapiens 92-121 31859592-5 2020 METHODS AND RESULTS: In this study, we identified FXa as potent, direct agonist of the PAR-1 (protease-activated receptor 1), leading to platelet activation and thrombus formation, which can be inhibited by rivaroxaban. Rivaroxaban 207-218 coagulation factor II thrombin receptor Homo sapiens 87-92 31859592-5 2020 METHODS AND RESULTS: In this study, we identified FXa as potent, direct agonist of the PAR-1 (protease-activated receptor 1), leading to platelet activation and thrombus formation, which can be inhibited by rivaroxaban. Rivaroxaban 207-218 coagulation factor II thrombin receptor Homo sapiens 94-123 28035779-9 2017 It is suggested that the relative downregulation of PAR-1 and PAR-2 by rivaroxaban compared with warfarin pretreatment might be partly involved in the mechanism of reduced hemorrhagic complications in patients receiving rivaroxaban in clinical trials. Rivaroxaban 220-231 coagulation factor II thrombin receptor Homo sapiens 52-57