PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35280252-12 2021 Conclusion: This study is the first to show that the CYP4F2 rs2074900 SNP had a remarkable effect on ticagrelor PK, which is significant since it adds to the limited pharmacogenetic information on ticagrelor. Ticagrelor 101-111 cytochrome P450 family 4 subfamily F member 2 Homo sapiens 53-59 35280252-12 2021 Conclusion: This study is the first to show that the CYP4F2 rs2074900 SNP had a remarkable effect on ticagrelor PK, which is significant since it adds to the limited pharmacogenetic information on ticagrelor. Ticagrelor 197-207 cytochrome P450 family 4 subfamily F member 2 Homo sapiens 53-59 31124413-4 2019 CYP4F2 T allele significantly increased odds for bleeding in ticagrelor users (OR: 8.270, 95% CI: 3.917-17.462; p < 0.001). Ticagrelor 61-71 cytochrome P450 family 4 subfamily F member 2 Homo sapiens 0-6 28604225-6 2017 CONCLUSION: Results of the current study showed that CYP4F2 rs3093135 TT variant carriers had a higher antiplatelet effect of ticagrelor, and more frequently had nonprocedural bleeding during ticagrelor therapy, as compared with AA and AT variant carriers. Ticagrelor 126-136 cytochrome P450 family 4 subfamily F member 2 Homo sapiens 53-59