PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33563204-0 2022 Ticagrelor Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats by Inhibition of TGF-beta1/Smad3 and PI3K/AKT/mTOR Pathways. Ticagrelor 0-10 AKT serine/threonine kinase 1 Rattus norvegicus 110-113 33957564-11 2021 In conclusion, ticagrelor reno-therapeutic effect is partly mediated through modulating the Epac-1/Rap-1-GTP, AKT/Nrf-2/HO-1 and JAK-2/STAT-3/SOCS-3 trajectories, pathways that integrate to afford novel explanations to its anti-inflammatory, anti-oxidant, and anti-apoptotic potentials. Ticagrelor 15-25 AKT serine/threonine kinase 1 Rattus norvegicus 110-113 33563204-11 2022 In addition, ticagrelor antagonized PI3K/AKT/mTOR pathway signaling. Ticagrelor 13-23 AKT serine/threonine kinase 1 Rattus norvegicus 41-44 26044583-9 2015 Ticagrelor, but not clopidogrel, increased myocardial adenosine levels, increased phosphorylation of Akt, endothelial NO synthase, and extracellular-signal-regulated kinase 1/2 4 hours after reperfusion and decreased apoptosis. Ticagrelor 0-10 AKT serine/threonine kinase 1 Rattus norvegicus 101-104