PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31274838-1	2019	We recently showed that ticagrelor reduced myocardial ischemia-reperfusion injury (IRI) and downregulated galectin-3 in the ischemic myocardium.	Ticagrelor	24-34	galectin 3	Rattus norvegicus	106-116	
31274838-4	2019	Ticagrelor significantly reduced the infarct size and plasma cTnI at 3 and 7 days after IRI, significantly downregulated protein and mRNA expressions of NF-kappaB and galectin-3, and mRNA expressions of IL-6 and TNF-alpha in the ischemic area at 24 hours, 3 and 7 days after IRI.	Ticagrelor	0-10	galectin 3	Rattus norvegicus	167-177	
29381821-4	2018	It remains unknown whether the cardioprotective effects of ticagrelor are also mediated by modulating myocardial galectin-3 expression.	Ticagrelor	59-69	galectin 3	Rattus norvegicus	113-123	
29381821-7	2018	RESULTS: Our results showed that ticagrelor treatment significantly reduced IA/AAR ratio at 3 and 7 days post I/R, downregulated mRNA and protein expression of galectin-3, as well as mRNA expression of TNF-alpha and IL-6 in infarct area at 24 h, 3 and 7 days post I/R.	Ticagrelor	33-43	galectin 3	Rattus norvegicus	160-170	
29381821-8	2018	CONCLUSIONS: Our results suggest that the cardioprotective effects of ticagrelor might partly be mediated by downregulating galectin-3 expression in infarct area in this rat model of myocardial I/R injury.	Ticagrelor	70-80	galectin 3	Rattus norvegicus	124-134