PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1906797-3	1991	The stimulatory effect of A-4166 on insulin release, in fasting dogs with a cannula into the portal vein, was more rapid than that of tolbutamide after oral administration.	Nateglinide	26-32	insulin	Canis lupus familiaris	36-43	
11979388-8	2002	An increase in plasma insulin level by nateglinide of 4 times basal (218 +/- 58 pmol/L v 47 +/- 3 pmol/L, P <.05, n = 6) occurred at 6 to 10 minutes followed by sustained release of 1.4 times basal (67 +/- 15 pmol/L, n = 6).	Nateglinide	39-50	insulin	Canis lupus familiaris	22-29	
11979388-12	2002	Lowering the primed doses of nateglinide resulted in a diminished peak plasma insulin concentration.	Nateglinide	29-40	insulin	Canis lupus familiaris	78-85	
11979388-14	2002	By increasing the continuous infusion of nateglinide, the sustained insulin release was not altered.	Nateglinide	41-52	insulin	Canis lupus familiaris	68-75	
11979388-18	2002	We conclude, therefore, that not only the different kinetics of gastrointestinal (GI) absorption, but also the inherent difference in the interaction with beta cells is attributed to the different insulin release characteristics between nateglinide and glibenclamide in vivo.	Nateglinide	237-248	insulin	Canis lupus familiaris	197-204