PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35084700-8	2022	Furthermore, treatment with Sal B down-regulated HG-induced PARP, cleaved-caspase 3, cleaved-caspase 9, Bax, NLRP3, ASC, and IL-1 beta expression, but mitigated HG-mediated down-regulation of Bcl-2 expression (P<0.05).	salvianolic acid B	28-33	BCL2, apoptosis regulator	Rattus norvegicus	192-197	
28852731-7	2016	RESULTS: Sal B significantly improved heart function and decreased infarct size; remarkably decreased levels of serum TNF-alpha and IL-Iotabeta levels, increased contents of myocardium antioxidant enzymes activities; western blot results showed that Sal B ameliorate the increased Bax and caspase-3 protins expressions and decreased Bcl-2 proteins expression and ratios of Bcl-2 to Bax.	salvianolic acid B	9-14	BCL2, apoptosis regulator	Rattus norvegicus	333-338	
28852731-7	2016	RESULTS: Sal B significantly improved heart function and decreased infarct size; remarkably decreased levels of serum TNF-alpha and IL-Iotabeta levels, increased contents of myocardium antioxidant enzymes activities; western blot results showed that Sal B ameliorate the increased Bax and caspase-3 protins expressions and decreased Bcl-2 proteins expression and ratios of Bcl-2 to Bax.	salvianolic acid B	9-14	BCL2, apoptosis regulator	Rattus norvegicus	373-378	
32010242-7	2020	Western blot analysis determined that Sal B treatment significantly decreased the expression of pro-apoptosis proteins, including Bax, cleaved caspase-3 and -9, in spinal cord tissues after SCI but enhanced the expression of Bcl-2, an anti-apoptotic protein.	salvianolic acid B	38-43	BCL2, apoptosis regulator	Rattus norvegicus	225-230	
28800882-0	2017	Salvianolic acid B inhibits intermittent high glucose-induced INS-1 cell apoptosis through regulation of Bcl-2 proteins and mitochondrial membrane potential.	salvianolic acid B	0-18	BCL2, apoptosis regulator	Rattus norvegicus	105-110	
28800882-8	2017	Taken together, these results indicate that Sal B is able to suppress intermittent high glucose-induced INS-1 cell apoptosis, which might be ascribed to regulation of Bcl-2 family protein expression and preservation of mitochondrial membrane potential.	salvianolic acid B	44-49	BCL2, apoptosis regulator	Rattus norvegicus	167-172	
27614127-7	2016	Sal B effectively reduced vascular endothelial cell apoptosis, with Bcl-2 protein up-regulated and Bax protein down-regulated markedly.	salvianolic acid B	0-5	BCL2, apoptosis regulator	Rattus norvegicus	68-73	
27139338-9	2016	Sal B inhibited the expression of Bax, cleaved caspase-9 and cleaved PARP, while promoted the expression of Bcl-2, LC3-II, Beclin1 and VEGF.	salvianolic acid B	0-5	BCL2, apoptosis regulator	Rattus norvegicus	108-113	
23201927-8	2013	In addition, the PI3K inhibitor partially blocked the effects of Sal B on the upregulation of Bcl-2 and Bcl-xl protein expression, and downregulation of Bax protein expression.	salvianolic acid B	65-70	BCL2, apoptosis regulator	Rattus norvegicus	94-99