PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30315526-0 2019 Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-kappaB and GRP78/PERK Pathways in Human Aorta Endothelial Cells. catalpol 0-8 NADPH oxidase 4 Homo sapiens 81-85 30315526-12 2019 TUDCA or Nox4 siRNA were used to investigate whether the effect of catalpol inhibiting the over-production of ROS were associated with inhibiting ER stress and Nox4 expression. catalpol 67-75 NADPH oxidase 4 Homo sapiens 160-164 30315526-17 2019 In addition, the extent of catalpol inhibiting ROS over-generation and NF-kappaB signaling pathway was reduced after inhibiting Nox4 or ER stress with DPI or TUDCA. catalpol 27-35 NADPH oxidase 4 Homo sapiens 128-132 29284152-11 2018 Taken together, these findings suggested that catalpol ameliorated hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway. catalpol 46-54 NADPH oxidase 4 Homo sapiens 136-140