PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33715230-0	2021	ATM inhibitor KU-55933 induces apoptosis and inhibits motility by blocking GLUT1-mediated glucose uptake in aggressive cancer cells with sustained activation of Akt.	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	14-22	solute carrier family 2 (facilitated glucose transporter), member 1	Mus musculus	75-80	
33715230-9	2021	KU-55933 treatment also inhibits tumor growth and metastasis in vivo in mouse mammary tumors through inhibition of GLUT1 translocation and vimentin expression.	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	0-8	solute carrier family 2 (facilitated glucose transporter), member 1	Mus musculus	115-120	
33715230-10	2021	These results suggest that ATM acts as a promoter of tumorigenesis in cancer cells with overactivated Akt, and KU-55933 induces apoptosis and inhibits motility by blocking GLUT1-mediated glucose uptake and glycolysis in these cancer cells, which may lead to the use of KU-55933 and its analogs as new preventive or therapeutic agents against cancer.	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	111-119	solute carrier family 2 (facilitated glucose transporter), member 1	Mus musculus	172-177	
33715230-10	2021	These results suggest that ATM acts as a promoter of tumorigenesis in cancer cells with overactivated Akt, and KU-55933 induces apoptosis and inhibits motility by blocking GLUT1-mediated glucose uptake and glycolysis in these cancer cells, which may lead to the use of KU-55933 and its analogs as new preventive or therapeutic agents against cancer.	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	269-277	solute carrier family 2 (facilitated glucose transporter), member 1	Mus musculus	172-177	
33715230-4	2021	In the present study, we found that aggressive breast and prostate cancer cell lines with overactivated Akt activity exhibit enhanced glucose uptake and GLUT1 translocation upon insulin treatment, and KU-55933, a specific inhibitor of ATM, inhibits insulin-mediated glucose uptake by blocking translocation of GLUT1 to the cell surface.	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	201-209	solute carrier family 2 (facilitated glucose transporter), member 1	Mus musculus	310-315