PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21325885-5	2011	Activation of ATM and CHEK2 occurred at the same time as this early arrest and was, like the arrest, abrogated by the ATM-inhibitor KU-55933.	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	132-140	checkpoint kinase 2	Homo sapiens	22-27	
24480460-5	2014	Treatment of cells overexpressing Aurora-A and ATM/Chk2 with the ATM specific inhibitor KU-55933 increased the cell sensitivity to cisplatin and irradiation through increasing the phosphorylation of p53 at Ser15 and inhibiting the expression of Chk2, gammaH2AX (Ser319), and RAD51.	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	88-96	checkpoint kinase 2	Homo sapiens	51-55	
24480460-5	2014	Treatment of cells overexpressing Aurora-A and ATM/Chk2 with the ATM specific inhibitor KU-55933 increased the cell sensitivity to cisplatin and irradiation through increasing the phosphorylation of p53 at Ser15 and inhibiting the expression of Chk2, gammaH2AX (Ser319), and RAD51.	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	88-96	checkpoint kinase 2	Homo sapiens	245-249	
25527123-10	2014	The S arrest and the activation of ATM-Chk1/Chk2-Cdc25A-Cdk2 pathways induced by SC-III3 in HepG2 cells could be efficiently abrogated by pretreatments of either Ku55933 (an inhibitor of ATM) or UCN-01 (an inhibitor of Chk1/Chk2).	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	162-169	checkpoint kinase 2	Homo sapiens	44-48	
25527123-10	2014	The S arrest and the activation of ATM-Chk1/Chk2-Cdc25A-Cdk2 pathways induced by SC-III3 in HepG2 cells could be efficiently abrogated by pretreatments of either Ku55933 (an inhibitor of ATM) or UCN-01 (an inhibitor of Chk1/Chk2).	2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one	162-169	checkpoint kinase 2	Homo sapiens	224-228