PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24643460-0 2014 Secreted frizzled related protein 1 modulates taxane resistance of human lung adenocarcinoma. taxane 46-52 secreted frizzled related protein 1 Homo sapiens 0-35 24643460-4 2014 Overexpression of SFRP1 reverses the chemoresistance of taxane-resistant LAD cell lines and enhances the in vivo sensitivity of taxane-resistant LAD cells to taxanes. taxane 56-62 secreted frizzled related protein 1 Homo sapiens 18-23 24643460-4 2014 Overexpression of SFRP1 reverses the chemoresistance of taxane-resistant LAD cell lines and enhances the in vivo sensitivity of taxane-resistant LAD cells to taxanes. taxane 128-134 secreted frizzled related protein 1 Homo sapiens 18-23 24643460-8 2014 Taken together, our results provide the direct evidence that SFRP1 is a clinically important determinant of taxanes resistance in human LAD cells, suggesting that SFRP1 might be a novel therapeutic target for the treatment of taxane-resistant LAD patients. taxane 108-114 secreted frizzled related protein 1 Homo sapiens 61-66 24643460-8 2014 Taken together, our results provide the direct evidence that SFRP1 is a clinically important determinant of taxanes resistance in human LAD cells, suggesting that SFRP1 might be a novel therapeutic target for the treatment of taxane-resistant LAD patients. taxane 108-114 secreted frizzled related protein 1 Homo sapiens 163-168 33224874-0 2020 miR-1260b Activates Wnt Signaling by Targeting Secreted Frizzled-Related Protein 1 to Regulate Taxane Resistance in Lung Adenocarcinoma. taxane 95-101 secreted frizzled related protein 1 Homo sapiens 47-82 33224874-9 2020 In clinical tumor tissue samples, high miR-1260b expression was detected in tumors of non-responding patients treated with taxane-based chemotherapy and was associated with low SFRP1 expression and poor prognosis. taxane 123-129 secreted frizzled related protein 1 Homo sapiens 177-182