PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9742213-0 1998 Chondrocyte-mediated catabolism of aggrecan: aggrecanase-dependent cleavage induced by interleukin-1 or retinoic acid can be inhibited by glucosamine. Glucosamine 138-149 ADAM metallopeptidase with thrombospondin type 1 motif, 4 Rattus norvegicus 45-56 9742213-8 1998 On the other hand, marked inhibition of aggrecanase-dependent cleavage was observed with both rat cells and bovine explants when d(+)-glucosamine was included at concentrations above 2 mM. Glucosamine 129-145 ADAM metallopeptidase with thrombospondin type 1 motif, 4 Rattus norvegicus 40-51 9742213-10 1998 Possible mechanisms for the inhibition of the aggrecanase response by glucosamine in chondrocytes treated with IL-1 or RA are discussed. Glucosamine 70-81 ADAM metallopeptidase with thrombospondin type 1 motif, 4 Rattus norvegicus 46-57