PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12135767-2	2002	The K(m)s for glucosamine and glucose of GLUT1 and GLUT4 were similar.	Glucosamine	14-25	solute carrier family 2 member 4	Homo sapiens	51-56	
20165829-7	2010	In both rat and human myotubes, glucosamine treatment reduced mRNA and protein levels of the gene encoding GLUT4 and mRNA levels of the main regulators of the gene encoding GLUT4 (myocyte enhancer factor 2 a [MEF2A] and peroxisome proliferator-activated receptor-gamma coactivator 1alpha [PGC1alpha]).	Glucosamine	32-43	solute carrier family 2 member 4	Homo sapiens	107-112	
20165829-7	2010	In both rat and human myotubes, glucosamine treatment reduced mRNA and protein levels of the gene encoding GLUT4 and mRNA levels of the main regulators of the gene encoding GLUT4 (myocyte enhancer factor 2 a [MEF2A] and peroxisome proliferator-activated receptor-gamma coactivator 1alpha [PGC1alpha]).	Glucosamine	32-43	solute carrier family 2 member 4	Homo sapiens	173-178	
20165829-8	2010	Again, PBA or TUDCA pretreatment prevented glucosamine-induced inhibition of GLUT4 (also known as SLC2A4), MEF2A and PGC1alpha (also known as PPARGC1A).	Glucosamine	43-54	solute carrier family 2 member 4	Homo sapiens	77-82	
20165829-8	2010	Again, PBA or TUDCA pretreatment prevented glucosamine-induced inhibition of GLUT4 (also known as SLC2A4), MEF2A and PGC1alpha (also known as PPARGC1A).	Glucosamine	43-54	solute carrier family 2 member 4	Homo sapiens	98-104	
12527361-3	2003	Consistent with a plasma membrane-localized effect, 3T3-L1 adipocytes exposed to glucosamine displayed an increase in cell-surface O-linked glycosylation and a simultaneously impaired mobilization of GLUT4 by insulin.	Glucosamine	81-92	solute carrier family 2 member 4	Homo sapiens	200-205	
12527361-7	2003	In conclusion, our data suggest that the mechanism by which glucosamine inhibits insulin-stimulated GLUT4 translocation involves modification of Munc18c.	Glucosamine	60-71	solute carrier family 2 member 4	Homo sapiens	100-105	
12527361-1	2003	Evidence suggests that glucosamine inhibits distal components regulating insulin-stimulated GLUT4 translocation to the plasma membrane.	Glucosamine	23-34	solute carrier family 2 member 4	Homo sapiens	92-97	
10644543-2	2000	In these cells, glucosamine impaired insulin-stimulated GLUT-4 translocation.	Glucosamine	16-27	solute carrier family 2 member 4	Homo sapiens	56-62	
11751846-13	2002	Chronically increased glucose flux or exposure to glucosamine disrupts this process, which may negatively impact the fusion of GLUT4-containing vesicles with the plasma membrane.	Glucosamine	50-61	solute carrier family 2 member 4	Homo sapiens	127-132	
11751589-0	2002	Ceramide and glucosamine antagonism of alternate signaling pathways regulating insulin- and osmotic shock-induced glucose transporter 4 translocation.	Glucosamine	13-24	solute carrier family 2 member 4	Homo sapiens	114-135	
10866051-18	2000	2) GlcN inhibited GLUT4 translocation, whereas high glucose impaired GLUT4 "intrinsic activity" or membrane intercalation.	Glucosamine	3-7	solute carrier family 2 member 4	Homo sapiens	18-23	
9685425-4	1998	Subcellular fractionation experiments demonstrated that reduction in insulin-stimulated 2-deoxyglucose uptake by glucosamine was due to an inhibition of translocation of both Glut 1 and Glut 4 from the low density microsomes (LDM) to the plasma membrane.	Glucosamine	113-124	solute carrier family 2 member 4	Homo sapiens	186-192	
9030547-8	1997	Finally, immunoisolation of GLUT4-containing vesicles revealed that the rate of labeled GlcN incorporation was approximately 100-fold greater following GlcN compared with saline infusions (p < 0.01).	Glucosamine	88-92	solute carrier family 2 member 4	Homo sapiens	28-33	
9030547-8	1997	Finally, immunoisolation of GLUT4-containing vesicles revealed that the rate of labeled GlcN incorporation was approximately 100-fold greater following GlcN compared with saline infusions (p < 0.01).	Glucosamine	152-156	solute carrier family 2 member 4	Homo sapiens	28-33	
9030547-9	1997	We suggest that the marked reduction in insulin action induced by GlcN and uridine is mediated by increased accumulation of muscle UDP-N-acetylhexosamines, perhaps via altered glycosylation of protein(s) in GLUT4-containing vesicles.	Glucosamine	66-70	solute carrier family 2 member 4	Homo sapiens	207-212	
25962562-11	2015	Cells with glucosamine-induced insulin-resistance exhibited a reduced expression of GLUT4 and dysfunction in GLUT4 translocation, as well as increased activation of PTEN and increased cell apoptosis.	Glucosamine	11-22	solute carrier family 2 member 4	Homo sapiens	84-89	
25962562-11	2015	Cells with glucosamine-induced insulin-resistance exhibited a reduced expression of GLUT4 and dysfunction in GLUT4 translocation, as well as increased activation of PTEN and increased cell apoptosis.	Glucosamine	11-22	solute carrier family 2 member 4	Homo sapiens	109-114	
22993875-5	2004	Among the different glucose transporters, GLUT2 and GLUT4 can also transport GlcN, and both of these isoforms are transcriptionally repressed by the p53 protein, a tumor suppressor protein that regulates the cell cycle and promotes apoptosis (3).	Glucosamine	77-81	solute carrier family 2 member 4	Homo sapiens	52-57	
22993875-6	2004	GLUT1 and GLUT4 exhibit a similar affinity for glucose and GlcN, but GLUT2 has an approximate 20-fold higher affinity for GlcN than for glucose (3).	Glucosamine	59-63	solute carrier family 2 member 4	Homo sapiens	10-15