PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19375915-0	2009	The inhibitory mechanism of a novel cationic glucosamine derivative against MMP-2 and MMP-9 expressions.	Glucosamine	45-56	matrix metallopeptidase 9	Homo sapiens	86-91	
19375915-2	2009	For the first time, we identified that a novel Glc derivative having quaternized amino functionality (QAGlc) suppresses MMP-9 and MMP-2, gelatinases in HT1080, human fibrosarcoma cells at 40microg/ml, following stimulation with PMA.	Glucosamine	47-50	matrix metallopeptidase 9	Homo sapiens	120-125	
16756968-3	2006	RESULTS: Gelatin zymography revealed that glucosamine sulfate could suppress MMP-2 secretion in chondral, meniscal and synovial cultures and also decrease MMP-9 production in synovial and meniscal cultures.	Glucosamine	42-61	matrix metallopeptidase 9	Homo sapiens	155-160	
17498959-1	2007	In the present study, sulfated glucosamine (SGlc) that has been reported to relieve joint pain and inflammation in many arthritis patients was studied for its inhibitory effects on MMP-2 and MMP-9 in human fibrosarcoma cells.	Glucosamine	31-42	matrix metallopeptidase 9	Homo sapiens	191-196	
16756968-4	2006	ELISA data also showed the suppressive effects of glucosamine sulfate on u-PA and PAI-1 production in synovial cultures at 48 h. CONCLUSIONS: Our data suggest that one of the therapeutic effects of glucosamine sulfate is to down-regulate the expressions of u-PA, PAI-1, MMP-2 and MMP-9 that underlie the destruction of articular cartilage in the early stage of OA, and therefore to delay the joint failure.	Glucosamine	50-69	matrix metallopeptidase 9	Homo sapiens	280-285	
16756968-4	2006	ELISA data also showed the suppressive effects of glucosamine sulfate on u-PA and PAI-1 production in synovial cultures at 48 h. CONCLUSIONS: Our data suggest that one of the therapeutic effects of glucosamine sulfate is to down-regulate the expressions of u-PA, PAI-1, MMP-2 and MMP-9 that underlie the destruction of articular cartilage in the early stage of OA, and therefore to delay the joint failure.	Glucosamine	198-217	matrix metallopeptidase 9	Homo sapiens	280-285	
16616490-0	2006	Carboxy derivatized glucosamine is a potent inhibitor of matrix metalloproteinase-9 in HT1080 cells.	Glucosamine	20-31	matrix metallopeptidase 9	Homo sapiens	57-83	
27562075-12	2016	CONCLUSION: In this study, we found a pronounced suppressive effect of glucosamine sulfate particularly on MMP-3 and also MMP-9 mRNA and protein levels in osteosarcoma cell lines in vitro.	Glucosamine	71-90	matrix metallopeptidase 9	Homo sapiens	122-127