PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34483914-3	2021	Remdesivir and cyclosporine also separately reduced IL-6 production induced by HCoV-OC43 in human lung fibroblasts MRC-5 cells with EC50 values of 224 +- 53 nM and 1,292 +- 352 nM, respectively; and synergistically reduced it when combined.	remdesivir	0-10	interleukin 6	Homo sapiens	52-56	
35378756-6	2022	Restricted expression of viral gRNA and sgRNA in CD169 + macrophages elicited a pro-inflammatory cytokine expression (TNFalpha, IL-6 and IL-1beta) in a RIG-I, MDA-5 and MAVS-dependent manner, which was suppressed by remdesivir pre- treatment.	remdesivir	216-226	interleukin 6	Homo sapiens	128-132	
34093539-5	2021	RDV also inhibited other pro-inflammatory genes including tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), IL-12, IL-1beta, and interferon-beta (IFN-beta), leading to the reduction of inflammatory factors release.	remdesivir	0-3	interleukin 6	Homo sapiens	99-112	
34093539-5	2021	RDV also inhibited other pro-inflammatory genes including tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), IL-12, IL-1beta, and interferon-beta (IFN-beta), leading to the reduction of inflammatory factors release.	remdesivir	0-3	interleukin 6	Homo sapiens	114-118	
33245731-8	2020	TMPRSS2, inflammatory cytokines G-CSF, M-CSF, IL-1alpha, IL-6 and MCP-1 are suppressed by MEKi alone or with remdesivir.	remdesivir	109-119	interleukin 6	Homo sapiens	57-61	
32793908-8	2020	TMPRSS2, inflammatory cytokines G-CSF, M- CSF, IL-1a, IL-6 and MCP-1 are suppressed by MEKi alone or in combination with remdesivir.	remdesivir	121-131	interleukin 6	Homo sapiens	54-58	
33012543-3	2020	Among those with mortality, an increased concentration of inflammatory biomarkers (interleukin-6 and C-reactive protein) was noted with a lack of response to interleukin-6 blockade, remdesivir, and/or convalescent plasma.	remdesivir	182-192	interleukin 6	Homo sapiens	83-96