PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30182439-0 2019 Celecoxib alleviates AKT/c-Met-triggered rapid hepatocarcinogenesis by suppressing a novel COX-2/AKT/FASN cascade. Celecoxib 0-9 fatty acid synthase Mus musculus 101-105 30182439-9 2019 In addition, celecoxib efficiently repressed the phosphor-Akt (Thr308)/fatty acid synthase (FASN) axis both in vivo and in vitro. Celecoxib 13-22 fatty acid synthase Mus musculus 71-90 30182439-9 2019 In addition, celecoxib efficiently repressed the phosphor-Akt (Thr308)/fatty acid synthase (FASN) axis both in vivo and in vitro. Celecoxib 13-22 fatty acid synthase Mus musculus 92-96 30182439-10 2019 Altogether, this study suggests that celecoxib exerts its antilipogenic efficacy by targeting a COX-2/AKT/FASN cascade, which contributes to its ability to delay hepatocarcinogenesis. Celecoxib 37-46 fatty acid synthase Mus musculus 106-110 19159447-10 2009 Addition of celecoxib, a selective COX-2 inhibitor, significantly decreased PGE2 secretion (p < 0.05) versus control, and also significantly decreased FAS activity (p < 0.05). Celecoxib 12-21 fatty acid synthase Mus musculus 154-157 19159447-11 2009 Unexpectedly, the combination of exogenous PGE2 and celecoxib further decreased the FAS activity compared to PGE2 alone or untreated controls. Celecoxib 52-61 fatty acid synthase Mus musculus 84-87