PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29769213-0 2018 Chemopreventive Efficacy of the Cyclooxygenase-2 (Cox-2) Inhibitor, Celecoxib, Is Predicted by Adenoma Expression of Cox-2 and 15-PGDH. Celecoxib 68-77 15-hydroxyprostaglandin dehydrogenase Homo sapiens 127-134 29769213-7 2018 However, subset analysis suggested that this lack of response to celecoxib was confined to those patients with 15-PGDH intact tumors who were also using cardioprotective aspirin.Conclusions: The expression of Cox-2 and 15-PGDH in pre-treatment adenomas provides predictive information in patients treated with celecoxib for prevention of colorectal adenomas.Impact: The results of this study show that Cox-2 and 15-PGDH are characteristics of colorectal adenomas that may be used to predict nonsteroidal anti-inflammatory drug chemoprevention efficacy. Celecoxib 310-319 15-hydroxyprostaglandin dehydrogenase Homo sapiens 219-226