PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22198321-5 2012 We herein demonstrated for the first time that HP could induce a significant increase in the expression of HIF-1alpha as well as iron uptake (TfR1 and DMT1) and release (ferroportin1) proteins, and thus increase tansferrin-bound iron (Tf-Fe) and non-transferrin-bound iron (NTBI) uptake and iron release in astrocytes. Hematoporphyrins 47-49 transferrin receptor Homo sapiens 142-146 22281055-3 2012 Here, we demonstrated for the first time that HP could induce a significant increase in the expression of HIF-1alpha as well as iron uptake (TfR1 and DMT1) and release (Fpn1) proteins and thus increase transferrin-bound iron (Tf-Fe) and non-transferrin-bound iron (NTBI) uptake and iron release, and also a progressive increase in cellular iron content in the cultured neurons. Hematoporphyrins 46-48 transferrin receptor Homo sapiens 141-145