PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27619837-9 2016 STATEMENT OF SIGNIFICANCE: Due to the low ability to cross the blood-brain barrier (BBB) and non-specific interactions with metal ions necessary for normal cellular processes of metal chelator or Abeta inhibitors, we created a novel gold nanoparticle-capped mesoporous silica (MSN-AuNPs)-based H2O2-responsive controlled release system for targeted delivery of the metal chelator CQ and AuNPs (Abeta inhibitor). mesoporous silica 258-275 amyloid beta precursor protein Homo sapiens 196-201