PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15935590-5 2005 After 1 month of therapy with AchEI (Donepezil), MCP-1 levels increased in each patient. Donepezil 37-46 C-C motif chemokine ligand 2 Homo sapiens 49-54 16445950-7 2006 Expression and production of MCP-1 and IL-4 were significantly increased in AD subjects under therapy with the AChEI Donepezil, compared to the same AD patients at time of enrollment (P < 0.001). Donepezil 117-126 C-C motif chemokine ligand 2 Homo sapiens 29-34 16445950-8 2006 Our data suggest another possible explanation for the ability of Donepezil [diethyl(3,5-di-ter-butyl-4-hydroxybenzyl)phosphonate] to delay the progression of AD; in fact, Donepezil may modulate MCP-1 and IL-4 production, which may reflect a general shift towards type Th0/Th2 cytokines which could be protective in AD disease. Donepezil 65-74 C-C motif chemokine ligand 2 Homo sapiens 194-199 16445950-8 2006 Our data suggest another possible explanation for the ability of Donepezil [diethyl(3,5-di-ter-butyl-4-hydroxybenzyl)phosphonate] to delay the progression of AD; in fact, Donepezil may modulate MCP-1 and IL-4 production, which may reflect a general shift towards type Th0/Th2 cytokines which could be protective in AD disease. Donepezil 171-180 C-C motif chemokine ligand 2 Homo sapiens 194-199