PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18300869-7 2008 Moreover, peroxisome proliferator-activated receptor (PPAR)gamma and phosphatidylinositol 3 (PI-3) kinase p85 expression and insulin-induced Akt phosphorylation were reduced in SHR cardiomyocytes, but were markedly restored when animals were treated with rosiglitazone for 14 days. Rosiglitazone 255-268 WAP four-disulfide core domain 15B Rattus norvegicus 69-97 12740178-8 2003 The effects of RSG on insulin secretion were blocked by a PI 3-kinase inhibitor, wortmannin. Rosiglitazone 15-18 WAP four-disulfide core domain 15B Rattus norvegicus 58-62 12740178-9 2003 CONCLUSION: The effects of RSG on insulin secretion could be mediated through an IRS-2-associated PI 3-kinase signaling pathway. Rosiglitazone 27-30 WAP four-disulfide core domain 15B Rattus norvegicus 98-102