PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25399210-7 2014 RESULTS: Rosiglitazone treatment increased creatinine clearance and plasma transferrin, and decreased urinary ACR, HbA1c, plasma TNF-alpha, ICAM-1, and serum lipid peroxide levels without affecting the altered lipid profile. Rosiglitazone 9-22 intercellular adhesion molecule 1 Rattus norvegicus 140-146 30682409-10 2019 Furthermore, rosiglitazone treatment inhibited TGF-beta and NF-kappaB pathway activation, decreased collagen I, collagen IV, alpha-SMA, MCP-1, ICAM-1, TNF-alpha, and IL-1beta expression, and increased E-cadherin expression in renal allograft tissues from the CRAD rats. Rosiglitazone 13-26 intercellular adhesion molecule 1 Rattus norvegicus 143-149 26047949-13 2015 Rosiglitazone pretreatment significantly decreased ICAM-1 mRNA upregulation, secretion of IL-6 protein, and phosphorylation of NF-kappaB-p65 and IkappaBalpha without decreasing CD40 mRNA expression. Rosiglitazone 0-13 intercellular adhesion molecule 1 Rattus norvegicus 51-57 19237016-10 2009 RESULTS: Prophylactic administration of rosiglitazone attenuated (1) serum amylase level; (2) myeloperoxidase activity of pancreatic and pulmonary tissue; (3) expression of tumor necrosis factor-alpha and ICAM-1 in pancreas and lung; (4) pancreas and lung pathological damage. Rosiglitazone 40-53 intercellular adhesion molecule 1 Rattus norvegicus 205-211 21125406-7 2011 Ros or Los reduced the renal expression of PCNA, TGF-beta, ATR1, and ICAM-1 in IgAN rats with nephrectomy. Rosiglitazone 0-3 intercellular adhesion molecule 1 Rattus norvegicus 69-75 19246972-8 2008 CONCLUSION: Rosiglitazone could definitely protect against the renal injury of diabetic rats, which may be partly associated with decreasing the expression of ICAM-1 in the renal tissue, reducing ICAM-1 productions in both serum and urine. Rosiglitazone 12-25 intercellular adhesion molecule 1 Rattus norvegicus 159-165 19246972-8 2008 CONCLUSION: Rosiglitazone could definitely protect against the renal injury of diabetic rats, which may be partly associated with decreasing the expression of ICAM-1 in the renal tissue, reducing ICAM-1 productions in both serum and urine. Rosiglitazone 12-25 intercellular adhesion molecule 1 Rattus norvegicus 196-202 16909611-0 2006 [Effects of rosiglitazone on the expression of beta1, integrin and ICAM-1 in high glucose-induced rat glomerular mesangial cells]. Rosiglitazone 12-25 intercellular adhesion molecule 1 Rattus norvegicus 67-73 16770837-8 2007 ADMA (30 microM) significantly increased the activity of NF-kappaB and elevated the levels of ICAM-1 and TNF-alpha, and pre-treatment with rosiglitazone (10 or 30 microM) markedly inhibited the increased activity of NF-kappaB and reduced the elevated levels of TNF-alpha and ICAM-1 induced by ADMA in cultured endothelial cells. Rosiglitazone 139-152 intercellular adhesion molecule 1 Rattus norvegicus 94-100 16770837-8 2007 ADMA (30 microM) significantly increased the activity of NF-kappaB and elevated the levels of ICAM-1 and TNF-alpha, and pre-treatment with rosiglitazone (10 or 30 microM) markedly inhibited the increased activity of NF-kappaB and reduced the elevated levels of TNF-alpha and ICAM-1 induced by ADMA in cultured endothelial cells. Rosiglitazone 139-152 intercellular adhesion molecule 1 Rattus norvegicus 275-281 17003451-7 2006 ELISA analysis revealed that the upregulated ICAM-1 expression in the diabetic rat retina was reduced by rosiglitazone treatment. Rosiglitazone 105-118 intercellular adhesion molecule 1 Rattus norvegicus 45-51 16909611-1 2006 OBJECTIVE: To observe the effects of PPARgamma activators thiazolidinediones (Rosiglitazone) on the expression of intercellular adhesion molecule-1 (ICAM-1) and beta1 integrin in high glucose-induced rat glomerular mesangial cells (GMC) in order to elucidate the relationship between PPARgamma and adhesion molecules. Rosiglitazone 78-91 intercellular adhesion molecule 1 Rattus norvegicus 114-147 16909611-1 2006 OBJECTIVE: To observe the effects of PPARgamma activators thiazolidinediones (Rosiglitazone) on the expression of intercellular adhesion molecule-1 (ICAM-1) and beta1 integrin in high glucose-induced rat glomerular mesangial cells (GMC) in order to elucidate the relationship between PPARgamma and adhesion molecules. Rosiglitazone 78-91 intercellular adhesion molecule 1 Rattus norvegicus 149-155 16909611-6 2006 Rosiglitazone can inhibit the expression of ICAM-1 and beta1 integrin in normal and high glucose treated GMCs, and the inhibition is stronger in high glucose treated-group, which is in a dose-dependent manner. Rosiglitazone 0-13 intercellular adhesion molecule 1 Rattus norvegicus 44-50 16123307-10 2005 Cremaster mRNA expression of vascular cell adhesion molecule-1 (VCAM-1) was reduced by 35% in RSG-treated animals (P < 0.01), whereas P- and E-selectin and intercellular adhesion molecule-1 (ICAM-1) were unchanged. Rosiglitazone 94-97 intercellular adhesion molecule 1 Rattus norvegicus 194-200 16307220-9 2005 RESULTS: Rosiglitazone pretreatment significantly attenuated the increases in W/D ratio, MPO activity and MDA levels, and reduced pulmonary overproduction of TNF-alpha and CINC-1 as well as expression of ICAM-1 following endotoxemia. Rosiglitazone 9-22 intercellular adhesion molecule 1 Rattus norvegicus 204-210 12840602-9 2003 Renal expression of ICAM-1 caused by I/R was reduced by rosiglitazone and ciglitazone which was reflected by decreased PMN infiltration into reperfused renal tissues. Rosiglitazone 56-69 intercellular adhesion molecule 1 Rattus norvegicus 20-26 12970094-19 2003 Administration of rosiglitazone and 15d-PGJ2 also markedly reduced the nitrotyrosine formation and the upregulation of ICAM-1 during reperfusion. Rosiglitazone 18-31 intercellular adhesion molecule 1 Rattus norvegicus 119-125 14709329-8 2004 Furthermore, rosiglitazone reduced: (1) the increase in the staining (immunohistochemistry) for nitrotyrosine and poly (ADP-ribose) polymerase (PARP), (2) the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), intercellular adhesion molecules-1 (ICAM-1) and P-selectin in the lungs of carrageenan-treated rats. Rosiglitazone 13-26 intercellular adhesion molecule 1 Rattus norvegicus 239-273 14709329-8 2004 Furthermore, rosiglitazone reduced: (1) the increase in the staining (immunohistochemistry) for nitrotyrosine and poly (ADP-ribose) polymerase (PARP), (2) the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), intercellular adhesion molecules-1 (ICAM-1) and P-selectin in the lungs of carrageenan-treated rats. Rosiglitazone 13-26 intercellular adhesion molecule 1 Rattus norvegicus 275-281