PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34781823-0 2021 Protein disulfide isomerase family 6 promotes the imatinib-resistance of renal cell carcinoma by regulation of Wnt3a-Frizzled1 axis. Imatinib Mesylate 50-58 Wnt family member 3A Homo sapiens 111-116 34781823-9 2021 Lastly, protein expression levels of Wnt3a and Frizzled1 (FZD1) in imatinib-resistant renal cell carcinoma cells were down-regulated by silencing of PDIA6. Imatinib Mesylate 67-75 Wnt family member 3A Homo sapiens 37-42 34781823-11 2021 In conclusion, knockdown of PDIA6 sensitized imatinib-resistant renal cell carcinoma cells to imatinib through inactivation of Wnt3a-FZD1 axis. Imatinib Mesylate 94-102 Wnt family member 3A Homo sapiens 127-132