PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35490598-5 2022 Transcript analysis of angiogenic factors of the vascular endothelial growth factor (VEGF) and matrix metalloproteinase (MMP) protein family demonstrated the ability of AEA to increase VEGF-C and VEGFR3 expression via cannabinoid receptors CB1 and CB2 while the placental growth factor (PlGF) was increased through CB1. aea 169-172 matrix metallopeptidase 2 Homo sapiens 121-124 22595113-5 2012 METHODS: We examined AEA-induced MMP-2 production and the expression of AEA receptors (cannabinoid [CB] receptor-1, CB2, and transient receptor potential vanilloid-1 [TRPV1]) in HPC by Western blot. aea 21-24 matrix metallopeptidase 2 Homo sapiens 33-38 22595113-8 2012 RESULTS: AEA significantly induced MMP-2 production in HPC. aea 9-12 matrix metallopeptidase 2 Homo sapiens 35-40 22595113-10 2012 AEA-induced MMP-2 production was blocked by CB1 or TRPV1 antagonists and by small interfering RNA for CB1 or TRPV1. aea 0-3 matrix metallopeptidase 2 Homo sapiens 12-17 22595113-12 2012 CONCLUSIONS: We demonstrated for the first time that AEA induced MMP-2 production via CB1 and TRPV1 in HPC. aea 53-56 matrix metallopeptidase 2 Homo sapiens 65-70