PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31298930-4 2019 Here, we show that agonist GW4064-mediated FXR activation inhibits the activity of the nonreceptor tyrosine kinase Src (proto-oncogene tyrosine-protein kinase), which is critical for regulation of yes-associated protein (YAP) phosphorylation and nuclear localization in renal fibrosis. GW 4064 27-33 yes-associated protein 1 Mus musculus 197-219 31298930-4 2019 Here, we show that agonist GW4064-mediated FXR activation inhibits the activity of the nonreceptor tyrosine kinase Src (proto-oncogene tyrosine-protein kinase), which is critical for regulation of yes-associated protein (YAP) phosphorylation and nuclear localization in renal fibrosis. GW 4064 27-33 yes-associated protein 1 Mus musculus 221-224 31298930-6 2019 Moreover, GW4064 treatment in HK2 cells increased Ser127 phosphorylation, cytosolic accumulation of YAP, and interaction of the hippo core kinases (Ste20-like kinase 1, large tumor suppressor kinase 1, and salvador homolog 1). GW 4064 10-16 yes-associated protein 1 Mus musculus 100-103