PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22583617-0	2012	E297G mutated bile salt export pump (BSEP) function enhancers derived from GW4064: structural development study and separation from farnesoid X receptor-agonistic activity.	GW 4064	75-81	ATP binding cassette subfamily B member 11	Homo sapiens	14-35	
22583617-0	2012	E297G mutated bile salt export pump (BSEP) function enhancers derived from GW4064: structural development study and separation from farnesoid X receptor-agonistic activity.	GW 4064	75-81	ATP binding cassette subfamily B member 11	Homo sapiens	37-41	
12519787-4	2003	Using real-time quantitative PCR and cotransfection reporter assays, we demonstrate that the RXR agonist LG100268 antagonizes induction of BSEP expression mediated by endogenous and synthetic FXR ligands, CDCA and GW4064, respectively.	GW 4064	214-220	ATP binding cassette subfamily B member 11	Homo sapiens	139-143	
26950211-12	2016	GCDCA-, CDCA- and GW4064- preconditioning enhanced ABCB11 mRNA levels, but in contrast to the bile acids, GW4064 did not significantly reduce GCDCA-induced caspase-3/7 activity.	GW 4064	18-24	ATP binding cassette subfamily B member 11	Homo sapiens	51-57	
22583617-3	2012	We previously found that compounds based on GW4064, a representative farnesoid X receptor (FXR) agonist, enhanced E297G BSEP transport activity.	GW 4064	44-50	ATP binding cassette subfamily B member 11	Homo sapiens	120-124	
22583617-4	2012	Here, we conducted a structure-activity relationship analysis of GW4064 derivatives aimed at separating E297G BSEP-function-promoting activity and FXR-agonistic activity.	GW 4064	65-71	ATP binding cassette subfamily B member 11	Homo sapiens	110-114	
22583617-5	2012	Among newly synthesized reversed-amide derivatives of previously reported GW4064 analogs 2a-2f, we identified 7c as a selective BSEP function enhancer.	GW 4064	74-80	ATP binding cassette subfamily B member 11	Homo sapiens	128-132	
12525500-5	2003	In HepG2 cells, in the presence of an FXR agonist such as chenodeoxycholate or GW4064, GS enhanced endogenous BSEP expression with a maximum induction of 400-500% that induced by an FXR agonist alone.	GW 4064	79-85	ATP binding cassette subfamily B member 11	Homo sapiens	110-114	
12052824-6	2002	Both the endogenous FXR agonist chenodeoxycholate (CDCA) and synthetic FXR ligand GW4064 effectively increased BSEP mRNA in both cell types.	GW 4064	82-88	ATP binding cassette subfamily B member 11	Homo sapiens	111-115