PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29668847-12	2018	Conditioned medium of GW4064-treated adipocytes activated AMPK-PGC-1alpha signalling and reduced hypoxia-induced cardiomyocyte apoptosis, all of which were attenuated by an adiponectin neutralizing anti-body.	GW 4064	22-28	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	63-73	
21493670-0	2011	Bile acid receptor agonist GW4064 regulates PPARgamma coactivator-1alpha expression through estrogen receptor-related receptor alpha.	GW 4064	27-33	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	44-72	
21493670-3	2011	In our effort to identify new regulators of PGC-1alpha expression, we found that GW4064, a widely used synthetic agonist for the nuclear bile acid receptor [farnesoid X receptor (FXR)] strongly enhances PGC-1alpha promoter reporter activity, mRNA, and protein expression.	GW 4064	81-87	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	44-54	
21493670-3	2011	In our effort to identify new regulators of PGC-1alpha expression, we found that GW4064, a widely used synthetic agonist for the nuclear bile acid receptor [farnesoid X receptor (FXR)] strongly enhances PGC-1alpha promoter reporter activity, mRNA, and protein expression.	GW 4064	81-87	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	203-213	
21493670-7	2011	Interestingly, FXR disruption alters GW4064 induction of PGC-1alpha mRNA in a tissue-dependent manner.	GW 4064	37-43	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	57-67	
21493670-8	2011	Using FXR-null [FXR knockout (FXRKO)] mice, we determined that GW4064 induction of PGC-1alpha expression is not affected in oxidative soleus muscles of FXRKO mice but is compromised in the FXRKO liver.	GW 4064	63-69	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	83-93	
18385139-7	2008	Treatment of mice with GW4064, a synthetic agonist for farnesoid X receptor, induced SHP expression and decreased both the recruitment of PGC-1alpha to the Cyp7A1 promoter and the fasting-induced expression of CYP7A1 mRNA.	GW 4064	23-29	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	138-148