PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32103979-12	2020	Moreover, Wnt/beta-catenin pathway inhibitor XAV939 could inhibit the expressions of c-myc, cyclin D1 and beta-catenin, but activator LiCl could promote their expression.	XAV939	45-51	cyclin D1	Homo sapiens	92-101	
30042033-11	2018	Besides, liraglutide induced an increase of beta-catenin, c-myc, and cyclin D1 levels, which could also be blocked in the presence of Xav939.	XAV939	134-140	cyclin D1	Homo sapiens	69-78	
30483745-7	2019	XAV-939, a small molecule that inhibits the Wnt/beta-catenin signaling pathway by facilitating beta-catenin degradation, lowered beta-catenin and cyclin D1 protein expression to an extent similar to AT-101.	XAV939	0-3	cyclin D1	Homo sapiens	146-155	
30483745-8	2019	XAV-939 alone resulted in G1/G0 phase arrest and further induced cell cycle arrest in combination with AT-101, suggesting that the beta-catenin/cyclin D1 signaling pathway mediated, at least in part, the cell cycle arrest induced by AT-101.	XAV939	0-7	cyclin D1	Homo sapiens	144-153	
27150989-4	2016	RESULTS: 20 micromol/L XAV-939 and 20 mmol/L LiCl could effectively inhibit and activate Wnt signalling pathway of HL-60 cells respectively, could significantly down- and up-regulate the expression of cyclinD1, TCF1 and c-Jun genes (P < 0.05) and proteins (P < 0.05); moreover, the number of CD10(+) HL-60 cells in these conditions was below 1%, no early apoptosis of HL-60 cells was found.	XAV939	23-26	cyclin D1	Homo sapiens	201-209