PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30042033-11 2018 Besides, liraglutide induced an increase of beta-catenin, c-myc, and cyclin D1 levels, which could also be blocked in the presence of Xav939. XAV939 134-140 cyclin D1 Homo sapiens 69-78 32103979-12 2020 Moreover, Wnt/beta-catenin pathway inhibitor XAV939 could inhibit the expressions of c-myc, cyclin D1 and beta-catenin, but activator LiCl could promote their expression. XAV939 45-51 cyclin D1 Homo sapiens 92-101 30483745-7 2019 XAV-939, a small molecule that inhibits the Wnt/beta-catenin signaling pathway by facilitating beta-catenin degradation, lowered beta-catenin and cyclin D1 protein expression to an extent similar to AT-101. XAV939 0-3 cyclin D1 Homo sapiens 146-155 30483745-8 2019 XAV-939 alone resulted in G1/G0 phase arrest and further induced cell cycle arrest in combination with AT-101, suggesting that the beta-catenin/cyclin D1 signaling pathway mediated, at least in part, the cell cycle arrest induced by AT-101. XAV939 0-7 cyclin D1 Homo sapiens 144-153 27150989-4 2016 RESULTS: 20 micromol/L XAV-939 and 20 mmol/L LiCl could effectively inhibit and activate Wnt signalling pathway of HL-60 cells respectively, could significantly down- and up-regulate the expression of cyclinD1, TCF1 and c-Jun genes (P < 0.05) and proteins (P < 0.05); moreover, the number of CD10(+) HL-60 cells in these conditions was below 1%, no early apoptosis of HL-60 cells was found. XAV939 23-26 cyclin D1 Homo sapiens 201-209