PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29156556-7 2017 Furthermore, the mTORC1 and Wnt/beta-catenin pathway-specific antagonist rapamycin and XAV939 (3,5,7,8-tetrahydro-2-[4-(trifluoromethyl)]-4H -thiopyrano[4,3-d]pyrimidin-4-one) both suppressed the proliferation of IPEC-J2 cells overexpressing CDX2, and that the combination of rapamycin and XAV939 had an additive effect. XAV939 87-93 caudal type homeobox 2 Sus scrofa 242-246 29156556-8 2017 Regardless of whether the cells were treated with rapamycin or XAV939 alone or in combination, both mTORC1 and Wnt/beta-catenin pathways were down-regulated, accompanied by a decrease in CDX2 expression. XAV939 63-69 caudal type homeobox 2 Sus scrofa 187-191