PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27624805-7 2017 Treatment with either XAV-939 or ICG-001 effectively inhibited activation of beta-catenin and downregulated mRNA expression of beta-catenin-targeted genes in TDI-asthmatic mice, paralleled by dramatically attenuated TDI-induced hyperresponsiveness and inflammation of the airway, alleviated airway goblet cell metaplasia and collagen deposition, decreased Th2 inflammation, as well as lower levels of TGFbeta1, VEGF, HMGB1, and IL-1beta. XAV939 22-29 transforming growth factor, beta 1 Mus musculus 401-409