PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21600196-3 2011 Sulfation of the GAG chain is key as evidenced by the renal agenesis phenotype in mice deficient in the HS biosynthetic enzyme, heparan sulfate 2-O sulfotransferase (Hs2st; an enzyme which catalyzes the 2-O-sulfation of uronic acids in heparan sulfate). Uronic Acids 220-232 heparan sulfate 2-O-sulfotransferase 1 Mus musculus 166-171 26075383-2 2015 In mammals HS is subjected to differential sulfation by fifteen different heparan sulfotransferase (HST) enzymes of which Hs2st uniquely catalyzes the sulfation of the 2-O position of the uronate in HS. Uronic Acids 188-195 heparan sulfate 2-O-sulfotransferase 1 Mus musculus 122-127