PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26900446-3 2016 Dermatan sulfate epimerase 1 (DS-epi1) is the predominant enzyme during the formation of iduronic acid residues in the glycosaminoglycan dermatan sulfate. Iduronic Acid 89-102 dermatan sulfate epimerase Homo sapiens 0-28 33815739-1 2021 Dermatan sulfate epimerase 1 (DS-epi1, EC 5.1.3.19) catalyzes the conversion of d-glucuronic acid to l-iduronic acid on the polymer level, a key step in the biosynthesis of the glycosaminoglycan dermatan sulfate. Iduronic Acid 101-116 dermatan sulfate epimerase Homo sapiens 0-28 33815739-1 2021 Dermatan sulfate epimerase 1 (DS-epi1, EC 5.1.3.19) catalyzes the conversion of d-glucuronic acid to l-iduronic acid on the polymer level, a key step in the biosynthesis of the glycosaminoglycan dermatan sulfate. Iduronic Acid 101-116 dermatan sulfate epimerase Homo sapiens 30-37 31972438-1 2020 Dermatan sulfate (DS) is a glycosaminoglycan (GAG) that is produced through the epimerization of the glucuronic acid on chondroitin sulfate into iduronic acid (IduA) by dermatan sulfate epimerase (DS-epi) 1 and 2. Iduronic Acid 145-158 dermatan sulfate epimerase Homo sapiens 169-195 29976758-1 2018 During the biosynthesis of chondroitin/dermatan sulfate (CS/DS), a variable fraction of glucuronic acid is converted to iduronic acid through the activities of two epimerases, dermatan sulfate epimerases 1 (DS-epi1) and 2 (DS-epi2). Iduronic Acid 120-133 dermatan sulfate epimerase Homo sapiens 207-221 29976758-2 2018 Previous in vitro studies indicated that without association with other enzymes, DS-epi1 activity produces structures that have only a few adjacent iduronic acid units. Iduronic Acid 148-161 dermatan sulfate epimerase Homo sapiens 81-88 29976758-8 2018 The cooperation of DS-epi1 with D4ST1 may therefore explain the processive mode of the formation of iduronic acid blocks. Iduronic Acid 100-113 dermatan sulfate epimerase Homo sapiens 19-26 31972438-1 2020 Dermatan sulfate (DS) is a glycosaminoglycan (GAG) that is produced through the epimerization of the glucuronic acid on chondroitin sulfate into iduronic acid (IduA) by dermatan sulfate epimerase (DS-epi) 1 and 2. Iduronic Acid 160-164 dermatan sulfate epimerase Homo sapiens 169-195 31972438-1 2020 Dermatan sulfate (DS) is a glycosaminoglycan (GAG) that is produced through the epimerization of the glucuronic acid on chondroitin sulfate into iduronic acid (IduA) by dermatan sulfate epimerase (DS-epi) 1 and 2. Iduronic Acid 160-164 dermatan sulfate epimerase Homo sapiens 197-212 27101845-5 2016 We demonstrate that DS-epi1 is important for the generation of isolated iduronic acid residues in chondroitin sulfate (CS)/DS proteoglycans in early Xenopus embryos. Iduronic Acid 72-85 dermatan sulfate epimerase Homo sapiens 20-27 26900446-3 2016 Dermatan sulfate epimerase 1 (DS-epi1) is the predominant enzyme during the formation of iduronic acid residues in the glycosaminoglycan dermatan sulfate. Iduronic Acid 89-102 dermatan sulfate epimerase Homo sapiens 30-37 19188366-6 2009 By using a short interfering RNA approach, we found that DS-epi2 and DS-epi1 are both involved in the biosynthesis of the iduronic acid blocks in fibroblasts and that DS-epi2 can also synthesize the hybrid structures. Iduronic Acid 122-135 dermatan sulfate epimerase Homo sapiens 69-76