PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35435623-8	2022	RESULTS: Patients with moderate to severe cancer pain taking oxycodone had significantly higher levels of IL-2, IL-4, IL-6, IL-10, TNF-alpha, and IFN-gamma than those in the control group (p < 0.001).	Oxycodone	61-70	tumor necrosis factor	Homo sapiens	131-140	
35435623-11	2022	Analgesic tolerance induced by long-term oxycodone use could be closely related to the consistent upregulation of IL-6 and TNF-alpha levels.	Oxycodone	41-50	tumor necrosis factor	Homo sapiens	123-132	
31185942-8	2019	Serum concentrations of TNF-alpha at 6 h (38.68 +- 10.49 vs 73.02 +- 16.27, P<0.001) and 24 h (43.12 +- 8.40 vs 74.00 +- 21.30, P<0.001) in the oxycodone group were lower than the sufentanil group.	Oxycodone	144-153	tumor necrosis factor	Homo sapiens	24-33	
31185942-9	2019	CONCLUSIONS: Preemptive oxycodone 0.1 mg/kg administration could effectively suppress visceral pain at 2 h and 4 h after surgery and had lower inflammatory marker, serum TNF-alpha, level when compared to equal dose of sufentanil.	Oxycodone	24-33	tumor necrosis factor	Homo sapiens	170-179