PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28474563-6 2017 Long-term exposure to morphine and oxycodone has proven to up-regulate the expression of ABC transporters, such as P-gp, BCRP and MRPs, at the BBB, which may lead to increased tolerance to the antinociceptive effects of such drugs. Oxycodone 35-44 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 121-125