PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10632469-2 1999 In an in vitro test, bovine intestine dermatan sulfate exhibited stronger effects on stimulation of heparin cofactor II and activation of Glu-plasminogen by tissue plasminogen activator. Dermatan Sulfate 38-54 serpin family D member 1 Bos taurus 100-119 1386167-8 1992 From these results, it was suggested that a endogenous thrombin inhibitor heparin cofactor II may be activated in the liquid phase by dermatan sulfate released from plasmin-stimulated vascular smooth muscle cells when the vascular is disrupted and plasma is exposed to extravessel. Dermatan Sulfate 134-150 serpin family D member 1 Bos taurus 74-93 18156656-1 2008 Dermatan sulfate is a glycosaminoglycan that selectively inhibits the action of thrombin through interaction with heparin cofactor II. Dermatan Sulfate 0-16 serpin family D member 1 Bos taurus 114-133 18156656-4 2008 Previous studies have showed that dermatan sulfate derived from porcine/bovine intestinal mucosa/skin or marine invertebrates is capable of stimulating heparin cofactor II-mediated thrombin inhibition in vitro. Dermatan Sulfate 34-50 serpin family D member 1 Bos taurus 152-171 18156656-7 2008 Heparin cofactor II/dermatan sulfate-mediated thrombin inhibition measured in vitro revealed activity comparable to or higher than the commercial standard with 2-fold differences observed between some tissues. Dermatan Sulfate 20-36 serpin family D member 1 Bos taurus 0-19 7676405-0 1995 Structural heterogeneity of dermatan sulfate chains: correlation with heparin cofactor II activating properties. Dermatan Sulfate 28-44 serpin family D member 1 Bos taurus 70-89 7676405-5 1995 The ability of DS crude preparation to activate the heparin cofactor II (HCII) mediated inhibition of thrombin depends on the relative amount of highly active DS chains; this activity is related to the overall charge of DS chains and particularly with the content of IdoUA-2-SO4-->GalNAc-4-SO4 and UA-->GalNAc-4,6-di-SO4 disaccharides. Dermatan Sulfate 15-17 serpin family D member 1 Bos taurus 52-71 7676405-5 1995 The ability of DS crude preparation to activate the heparin cofactor II (HCII) mediated inhibition of thrombin depends on the relative amount of highly active DS chains; this activity is related to the overall charge of DS chains and particularly with the content of IdoUA-2-SO4-->GalNAc-4-SO4 and UA-->GalNAc-4,6-di-SO4 disaccharides. Dermatan Sulfate 15-17 serpin family D member 1 Bos taurus 73-77 7676405-5 1995 The ability of DS crude preparation to activate the heparin cofactor II (HCII) mediated inhibition of thrombin depends on the relative amount of highly active DS chains; this activity is related to the overall charge of DS chains and particularly with the content of IdoUA-2-SO4-->GalNAc-4-SO4 and UA-->GalNAc-4,6-di-SO4 disaccharides. Dermatan Sulfate 159-161 serpin family D member 1 Bos taurus 52-71 7676405-5 1995 The ability of DS crude preparation to activate the heparin cofactor II (HCII) mediated inhibition of thrombin depends on the relative amount of highly active DS chains; this activity is related to the overall charge of DS chains and particularly with the content of IdoUA-2-SO4-->GalNAc-4-SO4 and UA-->GalNAc-4,6-di-SO4 disaccharides. Dermatan Sulfate 159-161 serpin family D member 1 Bos taurus 73-77 7676405-5 1995 The ability of DS crude preparation to activate the heparin cofactor II (HCII) mediated inhibition of thrombin depends on the relative amount of highly active DS chains; this activity is related to the overall charge of DS chains and particularly with the content of IdoUA-2-SO4-->GalNAc-4-SO4 and UA-->GalNAc-4,6-di-SO4 disaccharides. Dermatan Sulfate 159-161 serpin family D member 1 Bos taurus 52-71 7676405-5 1995 The ability of DS crude preparation to activate the heparin cofactor II (HCII) mediated inhibition of thrombin depends on the relative amount of highly active DS chains; this activity is related to the overall charge of DS chains and particularly with the content of IdoUA-2-SO4-->GalNAc-4-SO4 and UA-->GalNAc-4,6-di-SO4 disaccharides. Dermatan Sulfate 159-161 serpin family D member 1 Bos taurus 73-77