PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34850861-1 2021 Musculocontractural Ehlers-Danlos syndrome (mcEDS) is caused by generalized depletion of dermatan sulfate (DS) due to biallelic pathogenic variants in CHST14 encoding dermatan 4-O-sulfotransferase 1 (D4ST1) (mcEDS-CHST14). Dermatan Sulfate 89-105 carbohydrate sulfotransferase 14 Mus musculus 151-157 34850861-1 2021 Musculocontractural Ehlers-Danlos syndrome (mcEDS) is caused by generalized depletion of dermatan sulfate (DS) due to biallelic pathogenic variants in CHST14 encoding dermatan 4-O-sulfotransferase 1 (D4ST1) (mcEDS-CHST14). Dermatan Sulfate 89-105 carbohydrate sulfotransferase 14 Mus musculus 167-198 34850861-1 2021 Musculocontractural Ehlers-Danlos syndrome (mcEDS) is caused by generalized depletion of dermatan sulfate (DS) due to biallelic pathogenic variants in CHST14 encoding dermatan 4-O-sulfotransferase 1 (D4ST1) (mcEDS-CHST14). Dermatan Sulfate 89-105 carbohydrate sulfotransferase 14 Mus musculus 200-205 34850861-1 2021 Musculocontractural Ehlers-Danlos syndrome (mcEDS) is caused by generalized depletion of dermatan sulfate (DS) due to biallelic pathogenic variants in CHST14 encoding dermatan 4-O-sulfotransferase 1 (D4ST1) (mcEDS-CHST14). Dermatan Sulfate 89-105 carbohydrate sulfotransferase 14 Mus musculus 214-220 32730567-6 2021 Dermatan 4 sulfotransferase 1, which transfers sulfate to the C-4 hydroxyl group of N-acetylgalactosamine of DS, contributes to neuronal differentiation of mouse neural progenitor cells. Dermatan Sulfate 109-111 carbohydrate sulfotransferase 14 Mus musculus 0-29 32601684-1 2021 Loss-of-function variants in CHST14 cause a dermatan 4-O-sulfotransferase deficiency named musculocontractural Ehlers-Danlos syndrome-CHST14 (mcEDS-CHST14), resulting in complete depletion of the dermatan sulfate moiety of decorin glycosaminoglycan (GAG) chains, which is replaced by chondroitin sulfate. Dermatan Sulfate 196-212 carbohydrate sulfotransferase 14 Mus musculus 29-35 29206923-3 2018 Carbohydrate sulfotransferase 14/dermatan 4-O-sulfotransferase-1 (CHST14/D4ST1) is a critical enzyme for biosynthesis of dermatan sulfate, a side chain of various proteoglycans including biglycan that regulates collagen fibrils through their interaction. Dermatan Sulfate 121-137 carbohydrate sulfotransferase 14 Mus musculus 0-64 30853887-4 2019 It has been reported that dermatan 4-O-sulfotransferase-1 (Chst14/D4st1) specific for DS, but not chondroitin 4-O-sulfotransferase-1 (Chst11/C4st1) specific for CS, regulates proliferation and neurogenesis of neural stem cells (NSCs), indicating that CS and DS play distinct roles in the self-renewal and differentiation of NSCs. Dermatan Sulfate 86-88 carbohydrate sulfotransferase 14 Mus musculus 59-65 30853887-4 2019 It has been reported that dermatan 4-O-sulfotransferase-1 (Chst14/D4st1) specific for DS, but not chondroitin 4-O-sulfotransferase-1 (Chst11/C4st1) specific for CS, regulates proliferation and neurogenesis of neural stem cells (NSCs), indicating that CS and DS play distinct roles in the self-renewal and differentiation of NSCs. Dermatan Sulfate 86-88 carbohydrate sulfotransferase 14 Mus musculus 66-71 30853887-4 2019 It has been reported that dermatan 4-O-sulfotransferase-1 (Chst14/D4st1) specific for DS, but not chondroitin 4-O-sulfotransferase-1 (Chst11/C4st1) specific for CS, regulates proliferation and neurogenesis of neural stem cells (NSCs), indicating that CS and DS play distinct roles in the self-renewal and differentiation of NSCs. Dermatan Sulfate 258-260 carbohydrate sulfotransferase 14 Mus musculus 59-65 29206923-3 2018 Carbohydrate sulfotransferase 14/dermatan 4-O-sulfotransferase-1 (CHST14/D4ST1) is a critical enzyme for biosynthesis of dermatan sulfate, a side chain of various proteoglycans including biglycan that regulates collagen fibrils through their interaction. Dermatan Sulfate 121-137 carbohydrate sulfotransferase 14 Mus musculus 66-72 29206923-3 2018 Carbohydrate sulfotransferase 14/dermatan 4-O-sulfotransferase-1 (CHST14/D4ST1) is a critical enzyme for biosynthesis of dermatan sulfate, a side chain of various proteoglycans including biglycan that regulates collagen fibrils through their interaction. Dermatan Sulfate 121-137 carbohydrate sulfotransferase 14 Mus musculus 73-78 23360803-3 2013 To enable a novel approach in studies on DS versus CS roles during development and regeneration, we generated a mouse deficient in the dermatan 4-O-sulfotransferase1 (Chst14(-/-)), a key enzyme in the synthesis of iduronic acid-containing modules found in DS but not CS. Dermatan Sulfate 256-258 carbohydrate sulfotransferase 14 Mus musculus 167-173