PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22286447-12 2012 CONCLUSION: The authors" results indicate that silicone implants trigger a specific, antigen-driven local immune response through activated TH1/TH17 cells, suggesting that ensuing fibrosis is promoted by the production of profibrotic cytokines as a consequence of faltering function of local T regulatory cells. Silicones 47-55 negative elongation factor complex member C/D Homo sapiens 140-143