PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2106874-11 1990 It is suggested that tissue EC-SOD is secreted by a few well-dispersed cell types, such as fibroblasts and glia cells, to diffuse subsequently around and reversibly bind to heparan sulphate proteoglycan ligands in the glycocalyx of the surface of most tissue cell types and in the interstitial matrix. Heparitin Sulfate 173-189 superoxide dismutase 3 Homo sapiens 28-34 1505778-1 1992 The secretory enzyme extracellular-superoxide dismutase (EC-SOD) has affinity for heparin and some other sulfated glycosaminoglycans and is in vivo bound to heparan sulfate proteoglycan. Heparitin Sulfate 157-172 superoxide dismutase 3 Homo sapiens 21-55 1505778-1 1992 The secretory enzyme extracellular-superoxide dismutase (EC-SOD) has affinity for heparin and some other sulfated glycosaminoglycans and is in vivo bound to heparan sulfate proteoglycan. Heparitin Sulfate 157-172 superoxide dismutase 3 Homo sapiens 57-63 3476950-9 1987 This sequence probably confers the affinity of EC-SOD for heparin and heparan sulfate. Heparitin Sulfate 70-85 superoxide dismutase 3 Homo sapiens 47-53 2654474-9 1989 The findings are compatible with the notion that EC-SOD C in the vasculature forms an equilibrium between plasma and heparan sulfate in the glycocalyx of the endothelium. Heparitin Sulfate 117-132 superoxide dismutase 3 Homo sapiens 49-55 2654474-10 1989 Furthermore, tissue EC-SOD is probably distributed between heparan sulfate on the surface of most cell types in the organs and in the interstitial matrix. Heparitin Sulfate 59-74 superoxide dismutase 3 Homo sapiens 20-26 15362977-1 2005 The C-terminal region of EC-SOD (extracellular superoxide dismutase) mediates the binding to both heparin/heparan sulphate and type I collagen. Heparitin Sulfate 106-122 superoxide dismutase 3 Homo sapiens 25-31 15899505-2 2005 Extracellular SOD (EC-SOD/SOD3) is a major superoxide scavenger and it is located on cell surfaces and primarily in extracellular matrix, and binds heparan sulfates by its carboxyterminal portion. Heparitin Sulfate 148-164 superoxide dismutase 3 Homo sapiens 14-17 15899505-2 2005 Extracellular SOD (EC-SOD/SOD3) is a major superoxide scavenger and it is located on cell surfaces and primarily in extracellular matrix, and binds heparan sulfates by its carboxyterminal portion. Heparitin Sulfate 148-164 superoxide dismutase 3 Homo sapiens 19-25 15899505-2 2005 Extracellular SOD (EC-SOD/SOD3) is a major superoxide scavenger and it is located on cell surfaces and primarily in extracellular matrix, and binds heparan sulfates by its carboxyterminal portion. Heparitin Sulfate 148-164 superoxide dismutase 3 Homo sapiens 26-30 19602586-7 2009 We have further shown that overexpression of EcSOD decreased accumulation of vascular endothelial growth factor in the culture medium and increased the level of intact cell surface-associated heparan sulfate, thus implicating inhibition of heparanase expression as a potential mechanism. Heparitin Sulfate 192-207 superoxide dismutase 3 Homo sapiens 45-50 15362977-1 2005 The C-terminal region of EC-SOD (extracellular superoxide dismutase) mediates the binding to both heparin/heparan sulphate and type I collagen. Heparitin Sulfate 106-122 superoxide dismutase 3 Homo sapiens 33-67 15280800-3 2004 EC-SOD is a secretory, tetrameric glycoprotein containing copper and zinc, with a high affinity to certain glycosaminoglycans, such as heparin and heparan sulfate. Heparitin Sulfate 147-162 superoxide dismutase 3 Homo sapiens 0-6 11566193-1 2001 Extracellular-superoxide dismutase (EC-SOD) is bound to the vascular endothelial cell surface with an affinity for heparan sulfate proteoglycan. Heparitin Sulfate 115-130 superoxide dismutase 3 Homo sapiens 0-34 11557552-4 2001 The expression and secretion of EC-SOD were upregulated by histamine, vasopressin, oxytocin, endothelin-1, angiotensin II, serotonin, heparin, and heparan sulfate and were downregulated by platelet-derived growth factors-AA and -BB, acidic and basic fibroblast growth factors, and epidermal growth factor. Heparitin Sulfate 147-162 superoxide dismutase 3 Homo sapiens 32-38 12559606-4 2003 We have been using extracellular superoxide dismutase (EC-SOD) attached to the heparan sulfate on the endothelial cell surface as a marker of vascular damage. Heparitin Sulfate 79-94 superoxide dismutase 3 Homo sapiens 19-53 12559606-4 2003 We have been using extracellular superoxide dismutase (EC-SOD) attached to the heparan sulfate on the endothelial cell surface as a marker of vascular damage. Heparitin Sulfate 79-94 superoxide dismutase 3 Homo sapiens 55-61 11566193-1 2001 Extracellular-superoxide dismutase (EC-SOD) is bound to the vascular endothelial cell surface with an affinity for heparan sulfate proteoglycan. Heparitin Sulfate 115-130 superoxide dismutase 3 Homo sapiens 36-42 1477980-3 1992 EC-SOD is the major SOD isozyme in plasma and forms an equilibrium between the plasma phase and heparan sulfate proteoglycan on the surface of the endothelium. Heparitin Sulfate 96-111 superoxide dismutase 3 Homo sapiens 0-6 11437376-9 2001 In subendothelial space, EC-SOD bound on heparan sulfate might suppress LDL oxidation through reduction of superoxide anion. Heparitin Sulfate 41-56 superoxide dismutase 3 Homo sapiens 25-31 7705307-4 1994 One detrimental action of proteases released by adherent neutrophils may be the degradation of extracellular superoxide dismutase (ECSOD), which normally binds to the heparan sulfate on the surface the endothelium. Heparitin Sulfate 167-182 superoxide dismutase 3 Homo sapiens 95-129 7705307-4 1994 One detrimental action of proteases released by adherent neutrophils may be the degradation of extracellular superoxide dismutase (ECSOD), which normally binds to the heparan sulfate on the surface the endothelium. Heparitin Sulfate 167-182 superoxide dismutase 3 Homo sapiens 131-136 9464851-8 1997 While native EC-SOD shows high affinity for heparin and heparan sulphate, 90% of the EC-SOD in seminal plasma lacks the high affinity at ejaculation. Heparitin Sulfate 56-72 superoxide dismutase 3 Homo sapiens 13-19 8452552-3 1993 Heparin and dextran sulphate 5000 inhibited the proteolysis, suggesting that EC-SOD C sequestered by heparan sulphate proteoglycan in vivo is partially protected against proteolysis. Heparitin Sulfate 101-117 superoxide dismutase 3 Homo sapiens 77-83 8381106-1 1993 Extracellular-superoxide dismutase C (EC-SOD C) is a secretory tetrameric Cu- and Zn-containing glycoprotein which has high affinity for heparin and heparan sulfate. Heparitin Sulfate 149-164 superoxide dismutase 3 Homo sapiens 38-44 1477980-3 1992 EC-SOD is the major SOD isozyme in plasma and forms an equilibrium between the plasma phase and heparan sulfate proteoglycan on the surface of the endothelium. Heparitin Sulfate 96-111 superoxide dismutase 3 Homo sapiens 3-6