PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25828531-3 2015 report that trimming of heparan sulfate side chains of syndecans by endosomal heparanase facilitates sorting into exosomes by the formation of tight syndecan clusters that are recruited by the multivalent adaptor syntenin to the ALIX-ESCRT sorting machinery at endosomes. Heparitin Sulfate 24-39 programmed cell death 6 interacting protein Homo sapiens 229-233 25732677-10 2015 Taken together, our findings identify heparanase as a modulator of the syndecan-syntenin-ALIX pathway, fostering endosomal membrane budding and the biogenesis of exosomes by trimming the heparan sulfate chains on syndecans. Heparitin Sulfate 187-202 programmed cell death 6 interacting protein Homo sapiens 89-93