PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15372129-0	2004	Impact of cytochrome P-450 inhibition by cimetidine and induction by carbamazepine on the kinetics of hypericin and pseudohypericin in healthy volunteers.	hypericin	102-111	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	10-26	
10871299-9	2000	Hypericin also demonstrated potent inhibition of several CYP activities.	hypericin	0-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	57-60	
15638760-5	2005	In other contemporary studies, screening hypericin for inhibitory effects on various pharmaceutically important enzymes such as MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450), has yielded results supporting therapeutic potential.	hypericin	41-50	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	240-243	
15638760-5	2005	In other contemporary studies, screening hypericin for inhibitory effects on various pharmaceutically important enzymes such as MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450), has yielded results supporting therapeutic potential.	hypericin	41-50	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	245-260	
10871299-6	2000	In addition, three other constituents, hypericin, quercetin, and chlorogenic acid, were tested for inhibitory activity toward the CYP enzymes.	hypericin	39-48	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	130-133