PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9511735-2	1998	Our studies indicated that NaPA can impact on the RA differentiation program by upregulating nuclear retinoic acid receptor-beta (RAR beta) expression.	Acecainide	27-31	retinoic acid receptor beta	Homo sapiens	101-128	
9511735-2	1998	Our studies indicated that NaPA can impact on the RA differentiation program by upregulating nuclear retinoic acid receptor-beta (RAR beta) expression.	Acecainide	27-31	retinoic acid receptor beta	Homo sapiens	130-138	
9511735-4	1998	In contrast, NaPA was able to specifically activate a reporter gene construct (delta SV beta RE-CAT) which contains a retinoic acid response element (RARE beta) that is located in the RAR beta promoter.	Acecainide	13-17	retinoic acid receptor beta	Homo sapiens	184-192	
9511735-6	1998	Taken together, our findings suggest that induction of RAR beta by NaPA is regulated at the level of transcription and mediated through the retinoic acid response element, RARE beta.	Acecainide	67-71	retinoic acid receptor beta	Homo sapiens	55-63	
7829265-5	1995	We have determined that NaPA can markedly enhance mRNA levels of the nuclear RA receptor-beta (RAR beta) in LA-N-5 cells prior to morphologic or other phenotypic changes induced by this compound.	Acecainide	24-28	retinoic acid receptor beta	Homo sapiens	95-103	
7829265-7	1995	Thus among its varied effects on LA-N-5 cells, NaPA appears to interact with the RA pathway at the nuclear level by up-regulating RAR beta expression.	Acecainide	47-51	retinoic acid receptor beta	Homo sapiens	130-138